The 2021 Final Rule by CMS contains payment for physician and other billing professionals’ services under the Physician Fee Schedule. Because of budget neutrality the conversion factor has been set and well as the RVUS for certain services. Additional services involving Communications Technology have been added as well as the type of providers to use them. Direct supervision by Interactive Telecommunications Technology Remote Physiologic Monitoring Services (RPM) are explained. Outpatient Office/office Evaluation and management (E/M) have been changed with revision to the medical Table of Risk and time associated with these codes. Services of pharmacists and therapy assistants have been changed.